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Article

The -786 T/C polymorphism of NOS3 gene is a susceptibility marker of COPD among Tunisians that correlates with nitric oxide levels and airflow obstruction.

Cytokine - 1 May 2017

Ben Nasr Hela, Bchir Sarra, Ben Anes Amel, Amri Asma, Sakhana Yosra, Benzarti Mohamed, Garrouch Abdelhamid, Tabka Zouhair, Chahed Karim

Abstract excerpt

OBJECTIVE: The goal of this study was to examine the role of G894T (rs1799983), -786T/C (rs3918161) and a 27 bp variable number of tandem repeats (VNTR) 4B/4A of NOS3 gene on the risk and severity of COPD. METHODS: The study included 194 controls and 138 COPD patients. NOS3 G894T, -786T/C and 4B/4A variants were determined by PCR analysis based on the banding pattern on gel electrophoresis. Pulmonary function was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genetic Markers
Share to Genetic Predisposition to Disease
Share to Nitric Oxide
Share to Nitric Oxide Synthase Type III
Share to Polymorphism, Single Nucleotide
Share to Pulmonary Disease, Chronic Obstructive
Share to Tunisia

Source

Identifiers

PMID: 28526204
DOI: 10.1016/j.cyto.2017.05.010

Genes

NOS3
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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