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Article

Endothelial nitric oxide synthase gene polymorphisms are associated with sensitization to seasonal aeroallergens in asthmatic children.

World journal of pediatrics : WJP - 1 Feb 2017

Iordanidou Maria, Paraskakis Emmanouil, Tavridou Anna, Chatzimichael Athanasios, Manolopoulos Vangelis G

Abstract excerpt

BACKGROUND: Childhood asthma phenotype is the consequence of interaction between environment and genetic factors. Nitric oxide (NO) formation is affected by polymorphisms in nitric oxide synthase (NOS) enzymes, which play a significant role as inflammatory factors in the airways. This study was undertaken to estimate the correlation of -786C>T and 894G>T polymorphisms of the eNOS gene with the sensitization of...

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PMID: 27363984
DOI: 10.1007/s12519-016-0043-9

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