Article
Interleukin-2, interleukin-12, and interferon-gamma levels and risk of young adult Hodgkin lymphoma.
Blood - 1 Apr 2008
Cozen Wendy, Gill Parkash S, Salam Muhammad T, Nieters Alexandra, Masood Rizwan, Cockburn Myles G, Gauderman W James, Martínez-Maza Otoniel, Nathwani Bharat N, Pike Malcolm C, Van Den Berg David J, Hamilton Ann S, Deapen Dennis M, Mack Thomas M
Abstract excerpt
Young adult Hodgkin lymphoma (YAHL) is associated clinically with altered immunity, including a systemic defect in cell-mediated responses. There is strong evidence of a genetic contribution to risk, so we hypothesized that heritable alterations in cytokine production associated with Th1 function...
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