Article
Common genetic variants in proinflammatory and other immunoregulatory genes and risk for non-Hodgkin lymphoma.
Cancer research - 1 Oct 2006
Wang Sophia S, Cerhan James R, Hartge Patricia, Davis Scott, Cozen Wendy, Severson Richard K, Chatterjee Nilanjan, Yeager Meredith, Chanock Stephen J, Rothman Nathaniel
Abstract excerpt
Profound disruption of immune function is an established risk factor for non-Hodgkin lymphoma. We report here a large-scale evaluation of common genetic variants in immune genes and their role in lymphoma. We genotyped 57 single nucleotide polymorphisms (SNP) from 36 candidate immune genes in 1,172 non-Hodgkin lymphoma cases and 982 population-based controls from a US multicenter study. We calculated odds ratios...
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