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Article

Cytokine gene polymorphisms in multifactorial diseases: gateways to novel targets for immunotherapy?

Trends in pharmacological sciences - 1 Jun 2003

Vandenbroeck Koen, Goris An

Abstract excerpt

Recent advances in cytokine biology have led to novel approaches to the treatment of inflammatory diseases. In this article, we review recent data regarding the role of functional polymorphisms in the genes encoding the prototypic Th1 cytokine interferon gamma and Th2 cytokine interleukin 4 in multifactorial disorders. We have compared genetic data across a heterogeneous assortment of such conditions using a...

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PMID: 12823954
DOI: 10.1016/S0165-6147(03)00131-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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