Article
Cytokines in serum in relation to future non-Hodgkin lymphoma risk: evidence for associations by histologic subtype.
International journal of cancer - 15 Aug 2014
Edlefsen Kerstin L, Martínez-Maza Otoniel, Madeleine Margaret M, Magpantay Larry, Mirick Dana K, Kopecky Kenneth J, LaCroix Andrea Z, De Roos Anneclaire J
Abstract excerpt
Specific associations for lymphoma in the general population suggest that chronic immune dysfunction/dysregulation may be associated with the development of B-cell non-Hodgkin lymphoma (NHL). Furthermore, polymorphisms in several cytokine genes have been associated with increased lymphoma risk, most consistently with genes for TNF and IL10. To evaluate the hypothesis that prediagnostic circulating cytokine levels...
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