Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms and haplotypes of IL2RA, IL10, IFNG, IRF5, and CCR2 are associated with Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in children.

Pediatric blood & cancer - 1 Aug 2021

Tang Nannan, Huang Junbin, Chen Chun, Wu Xiaojun, Xu Honggui, Chen Guohua, Xue Hongman

Abstract excerpt

OBJECTIVE: Cytokine storms are central to the development of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis (EBV-HLH). Previous studies have shown that single-nucleotide polymorphisms (SNPs) of cytokine genes may be associated with the development of EBV-HLH in children. As such, we investigated the association between susceptibility to EBV-HLH in children and SNPs and haplotypes of genes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epstein-Barr Virus Infections
Share to Herpesvirus 4, Human

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interferon Regulatory Factors

Share to Interleukin-10

Share to Interleukin-2 Receptor alpha Subunit

Share to Lymphohistiocytosis, Hemophagocytic

Share to Receptors, CCR2

Share to Receptors, Chemokine

Source

Identifiers

PMID: 34031980
DOI: 10.1002/pbc.29097

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms and haplotypes of IL2RA, IL10, IFNG, IRF5, and CCR2 are associated with Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis in children.PMID 34031980Read ↗

[Relationship between Single Nucleotide Polymorphisms of IL2RA, IL-10 Gene and Epstein-Barr Virus Associated Hemophagocytic Lymphohistiocytosisin in children].Semantic proximity Read ↗

IL-10-592 A/C polymorphisms is associated with EBV-HLH in Chinese children.Semantic proximity Read ↗

Interferon gamma and interleukin 10 polymorphisms in Chinese children with hemophagocytic lymphohistiocytosis.Semantic proximity Read ↗

Biomarkers of pediatric Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis through single-cell transcriptomicsSemantic proximity Read ↗

Association of IRF5 polymorphisms with susceptibility to hemophagocytic lymphohistiocytosis in children.Semantic proximity Read ↗

[Association of CCR2 gene rs1799864 polymorphism with hemophagocytic lymphohistiocytosis in children].Semantic proximity Read ↗

Association of Interleukin-2-330T/G and Interleukin-10-1082A/G Genetic Polymorphisms with B-Cell Non-Hodgkin Lymphoma in a Cohort of Egyptians.Semantic proximity Read ↗

Cytokine gene polymorphisms and progression-free survival in classical Hodgkin lymphoma by EBV status: results from two independent cohorts.Semantic proximity Read ↗

Polymorphic variation of inflammation-related genes and risk of non-Hodgkin lymphoma for Uygur and Han Chinese in Xinjiang.Semantic proximity Read ↗

TLR4 896A/G and TLR9 1174G/A polymorphisms are associated with the risk of infectious mononucleosis.Semantic proximity Read ↗

Killer cell immunoglobulin-like receptor gene polymorphisms predispose susceptibility to Epstein-Barr virus associated hemophagocytic lymphohistiocytosis in Chinese children.Semantic proximity Read ↗

A Viral-Host Immunogenetic Interaction Model in Hodgkin Lymphoma: Co-Association of HHV-6B Infection and IL-18 rs1946518 Polymorphism.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.