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Article

IRF4 polymorphism rs872071 and risk of Hodgkin lymphoma.

British journal of haematology - 1 Feb 2010

Broderick Peter, Cunningham David, Vijayakrishnan Jayaram, Cooke Rosie, Ashworth Alan, Swerdlow Anthony, Houlston Richard

Abstract excerpt

The reciprocal familial risk between chronic lymphocytic leukaemia (CLL) and Hodgkin lymphoma (HL) suggests genetic variants with pleiotropic effects may influence the risk of both CLL and HL. We have recently shown that the IRF4 variant rs872071 influences CLL risk. To examine if rs872071 genotype is associated with HL risk we genotyped two case-control series (totalling, 529 and 2192, respectively). This...

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PMID: 19804451
DOI: 10.1111/j.1365-2141.2009.07946.x

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