Article
Cytokine gene polymorphisms and progression-free survival in classical Hodgkin lymphoma by EBV status: results from two independent cohorts.
Cytokine - 1 Nov 2013
Ghesquières Hervé, Maurer Matthew J, Casasnovas Olivier, Ansell Stephen M, Larrabee Beth R, Lech-Maranda Eva, Novak Anne J, Borrel Anne-Laure, Slager Susan L, Brice Pauline, Allmer Cristine, Brion Annie, Ziesmer Steven C, Morschhauser Franck, Habermann Thomas M, Gaillard Isabelle, Link Brian K, Stamatoullas Aspasia, Fermé Christophe, Dogan Ahmet, Macon William R, Audouin Josée, Cerhan James R, Salles Gilles
Abstract excerpt
BACKGROUND: Cytokines are important immune mediators of classical Hodgkin lymphoma (CHL) pathogenesis, and circulating levels at diagnosis may help predict prognosis. Germline single nucleotide polymorphisms (SNPs) in immune genes have been correlated with cytokine production and function. METHODS: We investigated whether selected germline SNPs in IL10 (rs1800890, rs1800896, rs1800871, rs1800872), TNFA...
