Ethnic distribution of slow acetylator mutations in the polymorphic N-acetyltransferase (NAT2) gene.

doi:10.1097/00008571-199406000-00003

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Article

Ethnic distribution of slow acetylator mutations in the polymorphic N-acetyltransferase (NAT2) gene.

Pharmacogenetics - 1 Jun 1994

Lin H J, Han C Y, Lin B K, Hardy S

Abstract excerpt

The acetylation polymorphism may affect rates of activation or detoxification of common carcinogens, thereby influencing cancer risk. Our aim was to define the ethnic distribution of the major slow acetylator mutations in the polymorphic N-acetyltransferase gene, in order to provide background da...

Topics

Acetylation
Adolescent
Adult
Alleles
Arylamine N-Acetyltransferase
Base Sequence
Biological Evolution
DNA Primers
Female
Gene Frequency
Humans
Infant, Newborn
Middle Aged
Molecular Sequence Data
Mutation
Polymerase Chain Reaction
Polymorphism, Genetic
Pregnancy

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