Article
Differences in N-acetylation genotypes between Caucasians and Black South Africans: implications for cancer prevention.
Cancer detection and prevention - 1 Jan 2002
Loktionov Alexandre, Moore William, Spencer Steven P, Vorster Hester, Nell Theo, O'Neill Ian K, Bingham Sheila A, Cummings John H
Abstract excerpt
Polymorphic N-acetyltransferase genes (NAT1 and NAT2) determine rapid or slow acetylation phenotypes, which are believed to affect cancer risk related to environmental exposure. Black South Africans have a unique incidence pattern of environment-related cancers, but genetic characteristics of this population are mostly unknown. In this study, we compared NAT1 and NAT2 allele distributions in 101 Black South...
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