Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interethnic and intraethnic variability of NAT2 single nucleotide polymorphisms.

Current drug metabolism - 1 Jul 2008

García-Martín Elena

Abstract excerpt

Genetic polymorphisms of human arylamine N-acetyltransferase 2 (NAT2) are responsible for interindividual variation in the acetylation of numerous drugs and in the transformation of aromatic and heterocyclic amines into carcinogenic intermediates. Although large interethnic variability in the frequency for NAT2 variant alleles has been reported, comparison of allele frequencies is hampered by differences in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ethnicity
Share to Arylamine N-Acetyltransferase
Share to NAT2 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 18680468
DOI: 10.2174/138920008784892155

Genes

NAT2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interethnic and intraethnic variability of NAT2 single nucleotide polymorphisms.PMID 18680468Read ↗

NAT2 global landscape: Genetic diversity and acetylation statuses from a systematic review.Semantic proximity Read ↗

Analysis of nucleotide diversity of NAT2 coding region reveals homogeneity across Native American populations and high intra-population diversity.Semantic proximity Read ↗

Molecular genetics and epidemiology of the NAT1 and NAT2 acetylation polymorphisms.Semantic proximity Read ↗

Population genetic diversity of the NAT2 gene supports a role of acetylation in human adaptation to farming in Central Asia.Semantic proximity Read ↗

Role of arylamine N-acetyltransferase 1 and 2 (NAT1 and NAT2) genotypes in susceptibility to oral/pharyngeal and laryngeal cancers.Semantic proximity Read ↗

Ethnic distribution of slow acetylator mutations in the polymorphic N-acetyltransferase (NAT2) gene.Semantic proximity Read ↗

Deciphering the ancient and complex evolutionary history of human arylamine N-acetyltransferase genes.Semantic proximity Read ↗

Arylamine N-acetyltransferase (NAT2) genotypes in a Turkish population.Semantic proximity Read ↗

A homogenizing process of selection has maintained an "ultra-slow" acetylation NAT2 variant in humans.Semantic proximity Read ↗

Arylamine N-acetyltransferase 2 polymorphism in the ethnic populations of South India.Semantic proximity Read ↗

N-acetyltransferase polymorphism among northern Sudanese.Semantic proximity Read ↗

Functional characterization of single-nucleotide polymorphisms and haplotypes of human N-acetyltransferase 2.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.