Article
Supratypes and ancestral haplotypes in IDDM: potential importance of central non-HLA MHC genes.
Journal of autoimmunity - 1 Apr 1990
Dawkins R L, Martin E, Saueracker G, Kay P H, Leaver A, Christiansen F T
Abstract excerpt
Juvenile insulin-dependent diabetes mellitus develops in susceptible children exposed to unknown environmental factors. If the genes responsible for susceptibility could be identified, it should be possible to understand the method of injury to beta cells as well as identify the infectious or other agents involved. For a decade it has been known that one or more of the susceptibility genes must be within the...
Topics
- Diabetes Mellitus, Type 1
- Genetic Predisposition to Disease
- Haplotypes
- Humans
- Major Histocompatibility Complex
