Article
Conservation of ancestral haplotypes telomeric of HLA-A.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Aug 1997
Tay G K, Cattley S K, Chorney M J, Hollingsworth P N, Roth M P, Dawkins R L, Witt C S
Abstract excerpt
Genes that predispose to haemochromatosis are though to be located within the several megabases telomeric of HLA-A. Further recombinant mapping has been used previously to map susceptibility genes for diseases such as insulin-dependent diabetes mellitus, myasthenia gravis and cystic fibrosis, and...
Topics
- B-Lymphocytes
- Cell Line, Transformed
- Chromosome Mapping
- Chromosomes, Human, Pair 6
- Genes, MHC Class I
- Genetic Predisposition to Disease
- HLA-A Antigens
- Haplotypes
- Humans
- Microsatellite Repeats
- Phenotype
- Recombination, Genetic
- Telomere
