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Article

Association of an IRF5 gene functional polymorphism with Sjögren's syndrome.

Arthritis and rheumatism - 1 Dec 2007

Miceli-Richard Corinne, Comets Emmanuelle, Loiseau Pascale, Puechal Xavier, Hachulla Eric, Mariette Xavier

Abstract excerpt

OBJECTIVE: Interferon regulatory factor 5 (IRF-5) is a transcription factor involved in the regulation of the host defense. Previous studies have demonstrated a significant association of various IRF5 gene polymorphisms with systemic lupus erythematosus (SLE) in Caucasians. The purpose of this case-control study was to investigate whether IRF5 polymorphisms are involved in the genetic predisposition to primary...

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Source

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Identifiers

PMID: 18050197
DOI: 10.1002/art.23142
PMCID: PMC3184606

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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