Association of a functional polymorphism in the IRF5 region with systemic sclerosis in a Japanese population.

doi:10.1002/art.24600

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Association of a functional polymorphism in the IRF5 region with systemic sclerosis in a Japanese population.

Arthritis and rheumatism - 1 Jun 2009

Ito Ikue, Kawaguchi Yasushi, Kawasaki Aya, Hasegawa Minoru, Ohashi Jun, Hikami Koki, Kawamoto Manabu, Fujimoto Manabu, Takehara Kazuhiko, Sato Shinichi, Hara Masako, Tsuchiya Naoyuki

Abstract excerpt

OBJECTIVE: Interferon regulatory factor 5, an established susceptibility factor for systemic lupus erythematosus (SLE), plays a role in type I interferon and proinflammatory cytokine induction. A recent study showed association of a functional single-nucleotide polymorphism (SNP) in intron 1 of IRF5, rs2004640, with systemic sclerosis (SSc) in a European French population. We undertook the present study to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Haplotypes

Share to Interferon Regulatory Factors

Share to Japan

Share to Polymorphism, Single Nucleotide

Share to RNA, Messenger

Share to Scleroderma, Systemic

Source

Open in PubMed

Identifiers

PMID: 19479858
DOI: 10.1002/art.24600

Genes

TNPO3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of a functional polymorphism in the IRF5 region with systemic sclerosis in a Japanese population.PMID 19479858Read ↗

Association of IRF5 polymorphisms with systemic lupus erythematosus in a Japanese population: support for a crucial role of intron 1 polymorphisms.Semantic proximity Read ↗

Association of the IRF5 SNP rs2004640 with Systemic Sclerosis in Han ChineseSemantic proximity Read ↗

Variants in the interferon regulatory factor 5 gene confer genetic risk for systemic lupus erythematosus in a Han Chinese population.Semantic proximity Read ↗

The systemic lupus erythematosus IRF5 risk haplotype is associated with systemic sclerosis.Semantic proximity Read ↗

Association between the IRF5 rs2004640 functional polymorphism and systemic sclerosis: a new perspective for pulmonary fibrosis.Semantic proximity Read ↗

A meta-analysis of the association of IRF5 polymorphism with systemic lupus erythematosus.Semantic proximity Read ↗

Polymorphisms in STAT4 and IRF5 increase the risk of systemic sclerosis: a meta-analysis.Semantic proximity Read ↗

Association between IRF5 polymorphisms and autoimmune diseases: a meta-analysis.Semantic proximity Read ↗

A single nucleotide polymorphism in the IRF5 promoter region is associated with susceptibility to rheumatoid arthritis in the Japanese population.Semantic proximity Read ↗

Interferon regulatory factor 5 polymorphisms in sarcoidosis.Semantic proximity Read ↗

Different genetic effects of interferon regulatory factor 5 (IRF5) polymorphisms on systemic lupus erythematosus in a Korean population.Semantic proximity Read ↗

Association between the rs2004640 functional polymorphism of interferon regulatory factor 5 and systemic lupus erythematosus: a meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.