Additive effects of the major risk alleles of IRF5 and STAT4 in primary Sjögren's syndrome.

doi:10.1038/gene.2008.94

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Article

Additive effects of the major risk alleles of IRF5 and STAT4 in primary Sjögren's syndrome.

Genes and immunity - 1 Jan 2009

Nordmark G, Kristjansdottir G, Theander E, Eriksson P, Brun J G, Wang C, Padyukov L, Truedsson L, Alm G, Eloranta M-L, Jonsson R, Rönnblom L, Syvänen A-C

Abstract excerpt

Primary Sjögren's syndrome (SS) shares many features with systemic lupus erythematosus (SLE). Here we investigated the association of the three major polymorphisms in IRF5 and STAT4 found to be associated with SLE, in patients from Sweden and Norway with primary SS. These polymorphisms are a 5-bp CGGGG indel in the promoter of IRF5, the single nucleotide polymorphism (SNP) rs10488631 downstream of IRF5 and the...

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PMID: 19092842
DOI: 10.1038/gene.2008.94

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STAT4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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