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Article

The GRIP1/14-3-3 pathway coordinates cargo trafficking and dendrite development.

Developmental cell - 24 Feb 2014

Geiger Julia C, Lipka Joanna, Segura Inmaculada, Hoyer Susanne, Schlager Max A, Wulf Phebe S, Weinges Stefan, Demmers Jeroen, Hoogenraad Casper C, Acker-Palmer Amparo

Abstract excerpt

Regulation of cargo transport via adaptor molecules is essential for neuronal development. However, the role of PDZ scaffolding proteins as adaptors in neuronal cargo trafficking is still poorly understood. Here, we show by genetic deletion in mice that the multi-PDZ domain scaffolding protein glutamate receptor interacting protein 1 (GRIP1) is required for dendrite development. We identify an interaction between...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24576423
DOI: 10.1016/j.devcel.2014.01.018

Genes

GRIP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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