Article

Neuronal connectivity, behavioral, and transcriptional alterations associated with the loss of MARK2

2023-12-07

Abstract excerpt

Neuronal connectivity is essential for adaptive brain responses and can be modulated by dendritic spine plasticity and the intrinsic excitability of individual neurons. Dysregulation of these processes can lead to aberrant neuronal activity, which has been associated with numerous neurological disorders including autism, epilepsy, and Alzheimer’s disease. Nonetheless, the molecular mechanisms underlying aberrant n...

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Literature Corpus work: 328628d5-64a0-5a2f-a623-c1f00195bf6a
DOI: 10.1101/2023.12.05.569759

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