Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lamin B1 protein is required for dendrite development in primary mouse cortical neurons.

Molecular biology of the cell - 1 Jan 2016

Giacomini Caterina, Mahajani Sameehan, Ruffilli Roberta, Marotta Roberto, Gasparini Laura

Abstract excerpt

Lamin B1, a key component of the nuclear lamina, plays an important role in brain development and function. A duplication of the human lamin B1 (LMNB1) gene has been linked to adult-onset autosomal dominant leukodystrophy, and mouse and human loss-of-function mutations in lamin B1 are susceptibility factors for neural tube defects. In the mouse, experimental ablation of endogenous lamin B1 (Lmnb1) severely...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Axons
Share to Dendrites
Share to Lamin Type B

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Mutant Strains

Share to Neurogenesis

Share to Neurons

Share to Nuclear Lamina

Share to Pregnancy

Source

Open in PubMed Open full text

Identifiers

PMID: 26510501
DOI: 10.1091/mbc.E15-05-0307
PMCID: PMC4694760

Genes

LMNB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lamin B1 protein is required for dendrite development in primary mouse cortical neurons.PMID 26510501Read ↗

LINCing lamin B2 to neuronal migration: growing evidence for cell-specific roles of B-type lamins.Semantic proximity Read ↗

Lamin B1 physically regulates neuronal migration by modulating nuclear deformability in the developing cortexSemantic proximity Read ↗

Lamin B1 mediates cell-autonomous neuropathology in a leukodystrophy mouse model.Semantic proximity Read ↗

Filamin A Regulates Neural Progenitor Proliferation and Cortical Size through Wee1-Dependent Cdk1 PhosphorylationSemantic proximity Read ↗

MARK1 regulates dendritic spine morphogenesis and cognitive functions <i>in vivo</i>Semantic proximity Read ↗

GRIP1 controls dendrite morphogenesis by regulating EphB receptor trafficking.Semantic proximity Read ↗

Persistent Lin28 Expression Impairs Neurite Outgrowth and Cognitive Function in the Developing Mouse Neocortex.Semantic proximity Read ↗

Cortical migration defects in mice expressing A-RAF from the B-RAF locus.Semantic proximity Read ↗

Filamin A in focus: unravelling the multifaceted roles of filamin A in neurodevelopment and neurological disordersSemantic proximity Read ↗

Polarity-regulating kinase partitioning-defective 1/microtubule affinity-regulating kinase 2 negatively regulates development of dendrites on hippocampal neurons.Semantic proximity Read ↗

Microtubule-Actin Crosslinking Factor 1 Is Required for Dendritic Arborization and Axon Outgrowth in the Developing Brain.Semantic proximity Read ↗

Nuclear envelope and lamin B2 function in the central nervous system.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.