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Article

Arp3 is required during preimplantation development of the mouse embryo.

FEBS letters - 11 Dec 2007

Vauti Franz, Prochnow Blair Raymond, Freese Elke, Ramasamy Suresh Kumar, Ruiz Patricia, Arnold Hans-Henning

Abstract excerpt

The role of Arp3 in mouse development was investigated utilizing a gene trap mutation in the Arp3 gene. Heterozygous Arp3(WT/GT) mice are normal, however, homozygous Arp3(GT/GT) embryos die at blastocyst stage. Earlier embryonic stages appear unaffected by the mutation, probably due to maternal Arp3 protein. Mutant blastocysts isolated at E3.5 fail to continue development in vitro, lack outgrowth of...

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PMID: 18035060
DOI: 10.1016/j.febslet.2007.11.031

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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