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Article

Atad3 function is essential for early post-implantation development in the mouse.

PloS one - 1 Jan 2013

Goller Tobias, Seibold Ursula K, Kremmer Elisabeth, Voos Wolfgang, Kolanus Waldemar

Abstract excerpt

The mitochondrial AAA+-ATPase ATAD3 is implicated in the regulation of mitochondrial and ER dynamics and was shown to be necessary for larval development in Caenorhabditis elegans. In order to elucidate the relevance of ATAD3 for mammalian development, the phenotype of an Atad3 deficient mouse line was analyzed. Atad3 deficient embryos die around embryonic day E7.5 due to growth retardation and a defective...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23372768
DOI: 10.1371/journal.pone.0054799
PMCID: PMC3556029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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