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Article

Lack of mutations in the TP53 tumor suppressor gene exons 5 to 8 in Fanconi's anemia.

Nouvelle revue francaise d'hematologie - 1 Jan 1991

Jonveaux P, Le Coniat M, Grausz D, Berger R

Abstract excerpt

The TP53 gene is considered to be a negative regulator of cell growth whose inactivation is an important step in the development or progression of malignancies. Recently, germ line TP53 mutations have been detected in a familial cancer syndrome, the dominantly inherited Li-Fraumeni syndrome. Using single strand conformation polymorphism analysis of PCR products, we looked for TP53 mutations in DNA of patients...

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PMID: 1803324

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lack of mutations in the TP53 tumor suppressor gene exons 5 to 8 in Fanconi's anemia.PMID 1803324Read ↗

Lack of mutations in the P53 gene exons 5 to 8 in ataxia-telangiectasia.Semantic proximity Read ↗

Absence of hereditary p53 mutations in 10 familial leukemia pedigrees.Semantic proximity Read ↗

Mutations of the p53 gene are not detectable in human testicular tumors.Semantic proximity Read ↗

Infrequent mutation of p53 gene in human renal cell carcinoma detected by polymerase chain reaction single-strand conformation polymorphism analysis.Semantic proximity Read ↗

Absence of germline mutations in exons 5-9 of the p53 gene in patients with Li-Fraumeni-like (SBLA) and familial adenomatous polyposis heritable cancer syndromes.Semantic proximity Read ↗

Significance of intron 6 sequence variations in the TP53 gene in Li-Fraumeni syndrome.Semantic proximity Read ↗

Investigation of single-strand conformational polymorphism of the TP53 gene in women with a family history of breast cancer.Semantic proximity Read ↗

Mutation of the tumor suppressor gene TP53 is not detected in psoriatic skin.Semantic proximity Read ↗

Absence of germline mutations of exons 5 to 8 of the P53 gene in 26 breast cancer families from the north of France.Semantic proximity Read ↗

Absence of TP53 alterations in pheochromocytomas and medullary thyroid carcinomas.Semantic proximity Read ↗

No TP53 mutations in neuroblastomas detected by PCR-SSCP analysis.Semantic proximity Read ↗

No evidence for germline mutations in exons 5-9 of the p53 gene in 25 breast cancer families.Semantic proximity Read ↗

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