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Article

Lack of mutations in the TP53 tumor suppressor gene exons 5 to 8 in Fanconi's anemia.

Nouvelle revue francaise d'hematologie - 1 Jan 1991

Jonveaux P, Le Coniat M, Grausz D, Berger R

Abstract excerpt

The TP53 gene is considered to be a negative regulator of cell growth whose inactivation is an important step in the development or progression of malignancies. Recently, germ line TP53 mutations have been detected in a familial cancer syndrome, the dominantly inherited Li-Fraumeni syndrome. Usin...

Topics

Aged
Base Sequence
Disease Susceptibility
Exons
Fanconi Anemia
Female
Genes, Tumor Suppressor
Humans
Leukemia
Male
Molecular Sequence Data
Mutation
Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

Source

Identifiers

PMID: 1803324

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1803324-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Lack of mutations in the TP53 tumor suppressor gene exons 5 to 8 in Fanconi's anemia.PMID 1803324Read ↗

Lack of mutations in the P53 gene exons 5 to 8 in ataxia-telangiectasia.Semantic proximity Read ↗

Absence of hereditary p53 mutations in 10 familial leukemia pedigrees.Semantic proximity Read ↗

Mutations of the p53 gene are not detectable in human testicular tumors.Semantic proximity Read ↗

Infrequent mutation of p53 gene in human renal cell carcinoma detected by polymerase chain reaction single-strand conformation polymorphism analysis.Semantic proximity Read ↗

Absence of germline mutations in exons 5-9 of the p53 gene in patients with Li-Fraumeni-like (SBLA) and familial adenomatous polyposis heritable cancer syndromes.Semantic proximity Read ↗

Significance of intron 6 sequence variations in the TP53 gene in Li-Fraumeni syndrome.Semantic proximity Read ↗

Investigation of single-strand conformational polymorphism of the TP53 gene in women with a family history of breast cancer.Semantic proximity Read ↗

Mutation of the tumor suppressor gene TP53 is not detected in psoriatic skin.Semantic proximity Read ↗

Absence of germline mutations of exons 5 to 8 of the P53 gene in 26 breast cancer families from the north of France.Semantic proximity Read ↗

Absence of TP53 alterations in pheochromocytomas and medullary thyroid carcinomas.Semantic proximity Read ↗

No TP53 mutations in neuroblastomas detected by PCR-SSCP analysis.Semantic proximity Read ↗

No evidence for germline mutations in exons 5-9 of the p53 gene in 25 breast cancer families.Semantic proximity Read ↗

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