Article
Mutation of the tumor suppressor gene TP53 is not detected in psoriatic skin.
The Journal of investigative dermatology - 1 Jul 1993
Molès J P, Theillet C, Basset-Sèguin N, Guilhou J J
Abstract excerpt
We investigated the tumor-suppressor gene, TP53, in psoriatic skin at gene (GP53) and protein (p53) levels. No mutation was detected in the seven exons analyzed using a combination of polymerase chain reaction and single-strand conformation polymorphism techniques. In addition, by immunohistochemistry using three different anti-p53 antibodies, no positive staining, reported to be associated with mutations and/or...
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