Absence of TP53 alterations in pheochromocytomas and medullary thyroid carcinomas.

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Article

Absence of TP53 alterations in pheochromocytomas and medullary thyroid carcinomas.

Genes, chromosomes & cancer - 1 Sept 1997

Herfarth K K, Wick M R, Marshall H N, Gartner E, Lum S, Moley J F

Abstract excerpt

The role of the TP53 gene in the development of inherited and sporadic pheochromocytomas and medullary thyroid carcinomas (MTC) has not been clarified because of conflicting reports and limitations in the assays used to detect mutations. To determine the frequency of TP53 alterations in these tum...

Topics

Adrenal Gland Neoplasms
Carcinoma, Medullary
Chromosome Aberrations
Chromosomes, Human, Pair 17
DNA Primers
DNA, Neoplasm
Genes, p53
Genetic Markers
Genotype
Heterozygote
Humans
Immunohistochemistry
Pheochromocytoma
Thyroid Neoplasms
Tumor Suppressor Protein p53

Source

Open in PubMed

Identifiers

PMID: 9290950

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9290950-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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