Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lack of mutations in the P53 gene exons 5 to 8 in ataxia-telangiectasia.

Cancer genetics and cytogenetics - 1 Apr 1993

Jonveaux P, Berger R

Abstract excerpt

Alterations of the TP53 tumor suppressor gene are present in various human malignancies and in the dominantly inherited Li-Fraumeni syndrome. Recently, a cell cycle checkpoint pathway involving p53 and GADD45 has been identified as defective in ataxia-telangiectasia. Using single strand conformation polymorphism analysis of PCR products, we looked for TP53 mutations in DNA of patients with AT. We did not find any...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ataxia Telangiectasia
Share to Base Sequence
Share to Exons

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, p53

Share to Molecular Sequence Data

Share to Mutation

Source

Identifiers

PMID: 8500101
DOI: 10.1016/0165-4608(93)90242-e

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lack of mutations in the P53 gene exons 5 to 8 in ataxia-telangiectasia.PMID 8500101Read ↗

Lack of mutations in the TP53 tumor suppressor gene exons 5 to 8 in Fanconi's anemia.Semantic proximity Read ↗

Reduced induction of P53 protein by gamma-irradiation in ataxia telangiectasia cells without constitutional mutations in exons 5, 6, 7, and 8 of the p53 gene.Semantic proximity Read ↗

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasiaSemantic proximity Read ↗

Absence of hereditary p53 mutations in 10 familial leukemia pedigrees.Semantic proximity Read ↗

Mutations of the p53 gene are not detectable in human testicular tumors.Semantic proximity Read ↗

Genetic alteration of p53 in some patients with adult T-cell leukemia.Semantic proximity Read ↗

Lack of mutation in exon 10 of p53 gene in thyroid tumors.Semantic proximity Read ↗

Infrequent mutations in the P53 gene in primary human T-cell acute lymphoblastic leukemia.Semantic proximity Read ↗

Infrequent mutation of p53 gene in human renal cell carcinoma detected by polymerase chain reaction single-strand conformation polymorphism analysis.Semantic proximity Read ↗

No TP53 mutations in neuroblastomas detected by PCR-SSCP analysis.Semantic proximity Read ↗

Mutation of the tumor suppressor gene TP53 is not detected in psoriatic skin.Semantic proximity Read ↗

Investigation of single-strand conformational polymorphism of the TP53 gene in women with a family history of breast cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.