[P53 protein gene. Review of the literature and assessment of the prognostic impact of its mutations in bladder tumors].

Abstract excerpt

The p53 protein, of the core protein group, was initially considered an oncogene but it was later noted to be included in the group of tumour-suppressive genes, the function of which seems to be focused in the control of cell growth, regulation of DNA transcription, and inhibition of certain oncogenes. A mutant protein variety has been observed with longer than normal mean life and altered function, so that it is...

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