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Article

Examination of IGF2 and H19 loss of imprinting in bladder cancer.

Cancer research - 15 Nov 2007

Byun Hyang-Min, Wong Hui-Lee, Birnstein Elliott Aaron, Wolff Erika M, Liang Gangning, Yang Allen S

Abstract excerpt

Loss of imprinting (LOI) is a common epigenetic event in cancer and may serve as an early biomarker in some cancers. To obtain a better understanding of LOI, we studied 41 bladder tumors and their adjacent normal bladder mucosa. We found 2/9 (22.2%) cases that displayed LOI of IGF2 and 2/16 (12.5%) that had LOI of H19, as determined by the evaluation of mRNA for biallelic expression. In addition, we examined...

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Share to Epigenesis, Genetic
Share to Genomic Imprinting
Share to Insulin-Like Growth Factor II

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intestinal Mucosa

Share to RNA, Long Noncoding

Share to RNA, Untranslated

Share to Urinary Bladder

Share to Urinary Bladder Neoplasms

Source

Identifiers

PMID: 18006818
DOI: 10.1158/0008-5472.CAN-07-0329

Genes

IGF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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