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Article

Insulin-like growth factor-2 (IGF2) loss of imprinting marks a field defect within human prostates containing cancer.

The Prostate - 1 Nov 2011

Bhusari Sachin, Yang Bing, Kueck Jessica, Huang Wei, Jarrard David F

Abstract excerpt

BACKGROUND: Loss of imprinting (LOI) is an epigenetic alteration involving loss of parental origin-specific expression at normally imprinted genes. A LOI for IGF2, a paracrine growth factor, has been implicated in the development of prostate and other cancers. In the current study, we define IGF2 LOI in histologically normal prostate tissues in relationship to tumor foci and gene expression. METHODS:...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21432864
DOI: 10.1002/pros.21379
PMCID: PMC3825178

Genes

IGF2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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