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Article

Insulin-like growth factor-2 (IGF2) loss of imprinting marks a field defect within human prostates containing cancer.

The Prostate - 1 Nov 2011

Bhusari Sachin, Yang Bing, Kueck Jessica, Huang Wei, Jarrard David F

Abstract excerpt

BACKGROUND: Loss of imprinting (LOI) is an epigenetic alteration involving loss of parental origin-specific expression at normally imprinted genes. A LOI for IGF2, a paracrine growth factor, has been implicated in the development of prostate and other cancers. In the current study, we define IGF2...

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Share to Gene Expression Regulation, Neoplastic
Share to Genomic Imprinting
Share to Insulin-Like Growth Factor II

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Reverse Transcriptase Polymerase Chain Reaction

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Source

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Identifiers

PMID: 21432864
DOI: 10.1002/pros.21379
PMCID: PMC3825178

Genes

IGF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-21432864-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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