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Article

The prevalence of loss of imprinting of H19 and IGF2 at birth.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Aug 2013

Rancourt Rebecca C, Harris Holly R, Barault Ludovic, Michels Karin B

Abstract excerpt

Imprinted genes are monoallelically expressed according to the parent of origin and are critical for proper placental and embryonic development. Disruption of methylation patterns at imprinted loci resulting in loss of imprinting (LOI) may lead to serious imprinting disorders (e.g., Beckwith-Wiedemann syndrome) and is described in some cancers (e.g., Wilms' tumor). As most research has focused on children with...

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Share to DNA Methylation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Infant, Newborn

Share to Insulin-Like Growth Factor II

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Source

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Identifiers

PMID: 23620526
DOI: 10.1096/fj.12-225284
PMCID: PMC3714582

Genes

IGF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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