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Article

Loss of imprinting of igf2 in renal-cell carcinomas.

International journal of cancer - 30 Jan 1998

Oda H, Kume H, Shimizu Y, Inoue T, Ishikawa T

Abstract excerpt

Loss of imprinting (LOI) of the igf2 and h19 genes has been found not only in embryonal tumors but also in common adult cancers. To determine any possible role of genomic imprinting in the development of renal-cell carcinomas (RCCs), we examined the imprinting status of igf2 and h19 in a series o...

Topics

Adult
Aged
Alleles
Carcinoma, Renal Cell
Female
Genomic Imprinting
Humans
Insulin-Like Growth Factor II
Kidney Neoplasms
Male
Middle Aged
Muscle Proteins
RNA, Long Noncoding

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 9455791
DOI: 10.1002/(sici)1097-0215(19980130)75:3<343::aid-ijc3>3.0.co;2-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9455791-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Loss of imprinting of igf2 in renal-cell carcinomas.PMID 9455791Read ↗

Frequent loss of imprinting of the H19 and IGF-II genes in ovarian tumors.Semantic proximity Read ↗

Loss of imprinting in hepatoblastoma.Semantic proximity Read ↗

Loss of imprinting of the insulin-like growth factor II gene in renal cell carcinoma.Semantic proximity Read ↗

Imprinting and expression of insulin-like growth factor-II and H19 in normal breast tissue and breast tumor.Semantic proximity Read ↗

[The aberrant imprinting of insulin-like growth factor II and H19 in human hepatocellular carcinoma].Semantic proximity Read ↗

Genomic imprinting of H19 and insulin-like growth factor-2 in pediatric germ cell tumorsSemantic proximity Read ↗

High incidence of loss of heterozygosity and abnormal imprinting of H19 and IGF2 genes in invasive cervical carcinomas. Uncoupling of H19 and IGF2 expression and biallelic hypomethylation of H19.Semantic proximity Read ↗

IGF2 but not H19 shows loss of imprinting in human glioma.Semantic proximity Read ↗

Loss of Imprinting of Insulin-Like Growth Factor-II (IGF2) Gene in Distinguishing Specific Biologic Subtypes of Wilms TumorSemantic proximity Read ↗

Epigenetic changes encompassing the IGF2/H19 locus associated with relaxation of IGF2 imprinting and silencing of H19 in Wilms tumor.Semantic proximity Read ↗

Loss of imprinting and overexpression of IGF2 gene in gastric adenocarcinoma.Semantic proximity Read ↗

Igf2-H19, an imprinted tandem gene, is an important regulator of embryonic development, a guardian of proliferation of adult pluripotent stem cells, a regulator of longevity, and a ‘passkey’ to cancerogenesisSemantic proximity Read ↗

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