IGF2 but not H19 shows loss of imprinting in human glioma.

Article

IGF2 but not H19 shows loss of imprinting in human glioma.

Cancer research - 1 Dec 1996

Uyeno S, Aoki Y, Nata M, Sagisaka K, Kayama T, Yoshimoto T, Ono T

Abstract excerpt

Genomic imprinting is a gamete-specific modification resulting in the allele-specific expression of genes in somatic cells. A loss of imprinting (LOI) has been found in many embryonal and adult tumors, suggesting that it plays a role in tumor development. The incidence of LOI, however, does not s...

Topics

Adult
Alleles
Brain Neoplasms
Child
Female
Frontal Lobe
Gene Expression Regulation, Neoplastic
Genomic Imprinting
Glioma
Humans
Insulin-Like Growth Factor II
Male
Middle Aged
Muscle Proteins
Neoplasm Proteins
RNA, Long Noncoding
RNA, Untranslated

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