Article
Frequent loss of imprinting of the H19 and IGF-II genes in ovarian tumors.
American journal of medical genetics - 4 Dec 1998
Kim H T, Choi B H, Niikawa N, Lee T S, Chang S I
Abstract excerpt
Several human imprinted genes have been identified and are implicated in genetic diseases and tumorigenesis. We studied alterations of two imprinted genes, the paternally imprinted H19 and maternally imprinted IGF2, in 15 ovarian tumors with various cell types. To know allele-specific expression...
Topics
- Alleles
- DNA, Neoplasm
- Female
- Gene Expression Regulation, Neoplastic
- Genes, Tumor Suppressor
- Genomic Imprinting
- Humans
- Insulin-Like Growth Factor II
- Muscle Proteins
- Ovarian Neoplasms
- Polymorphism, Restriction Fragment Length
- RNA, Long Noncoding
- RNA, Untranslated