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Article

Matrix metalloproteinase single-nucleotide polymorphisms and haplotypes predict breast cancer progression.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Nov 2007

Hughes Simon, Agbaje Olorunsola, Bowen Rebecca L, Holliday Deborah L, Shaw Jacqueline A, Duffy Stephen, Jones J Louise

Abstract excerpt

PURPOSE: Polymorphisms within the promoter region of several matrix metalloproteinase (MMP) genes have been linked to alterations in the level of transcription. We hypothesized that an individual's MMP genotype and haplotype will influence breast tumor progression and help predict prognosis. EXPERIMENTAL DESIGN: This study has evaluated the association between single-nucleotide polymorphisms (SNP) in the promoter...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18006768
DOI: 10.1158/1078-0432.CCR-07-0884

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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