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Article

Single nucleotide polymorphisms in MMP1 and MMP3 gene promoters as risk factor in head and neck squamous cell carcinoma.

Anticancer research - 1 Jan 2000

Zinzindohoué Franck, Blons Hélène, Hans Stéphane, Loriot Marie-Anne, Houllier Anne-Marie, Brasnu Daniel, Laccourreye Ollivier, Tregouet David-Alexandre, Stucker Isabelle, Laurent-Puig Pierre

Abstract excerpt

Matrix metalloproteinase (MMP) 1 and 3 genes play an important role in initiating tumor growth and promoting cell spread. Since MMP1 and MMP3 transcription levels can be modulated by promoter polymorphism, we investigated the impact of different genotypes on the occurrence of head and neck cancer in a Caucasian case control study. DNA was extracted from 126 male head and neck cancer patients and from 249 male...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15274394

Genes

MMP3
MMP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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