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Article

Association of matrix metalloproteinase-8 gene variation with breast cancer prognosis.

Cancer research - 1 Nov 2007

Decock Julie, Long Ji-Rong, Laxton Ross C, Shu Xiao-Ou, Hodgkinson Conrad, Hendrickx Wouter, Pearce Eve G, Gao Yu-Tang, Pereira Andresa C, Paridaens Robert, Zheng Wei, Ye Shu

Abstract excerpt

Animal and cell studies indicate an inhibitory effect of matrix metalloproteinase-8 (MMP8) on tumorigenesis and metastasis. We investigated whether MMP8 gene variation was associated with breast cancer metastasis and prognosis in humans. We first studied nine tagging single nucleotide polymorphisms (SNP) in the MMP8 gene in 140 clinically and pathologically well-characterized breast cancer patients. Four of the...

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PMID: 17974962
DOI: 10.1158/0008-5472.CAN-07-1683

Genes

MMP8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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