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Identification and functional analysis of exonic SNPs in MMP2 and MMP3 genes as prognostic biomarkers for breast cancer patients.

Molecular genetics and genomics : MGG - 4 Mar 2026

Chan Soon-Choy, Chin Fee-Wai, Noor Akmal Sharifah, Abdul Rahman Sabariah, Rosli Rozita

Abstract excerpt

Breast cancer is the most prevalent malignancy among women worldwide, and metastasis remains the leading cause of breast cancer-related deaths. Matrix metallopeptidase genes MMP2 and MMP3 are key regulators of extracellular matrix degradation and tumour invasion, yet the role of their exonic single nucleotide polymorphisms (SNPs) in breast cancer progression remains unexplored. This study aimed to identify exonic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41779051
DOI: 10.1007/s00438-026-02370-x

Genes

MMP3
MMP2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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