Impacts of Matrix Metalloproteinase-2 Promoter Genotypes on Breast Cancer Risk.

doi:10.21873/cgp.20467

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Back to search

Article

Impacts of Matrix Metalloproteinase-2 Promoter Genotypes on Breast Cancer Risk.

Cancer genomics & proteomics - 1 Jan 2000

Hung Chih-Chiang, Tsai Chung-Lin, Chin Yu-Ting, Wang Yun-Chi, Liu Chia-Hua, Lin Meng-Liang, Chen Shih-Shun, He Jie-Long, Tsai Chia-Wen, Su Chen-Hsien, Bau DA-Tian, Chang Wen-Shin

Abstract excerpt

BACKGROUND/AIM: Matrix metalloproteinase-2 (MMP-2) has been implicated in the pathogenesis of breast cancer (BC). However, there is limited research on the role of MMP-2 genotypes in BC risk. This study aimed to investigate the associations between two MMP-2 promoter polymorphisms, rs243865 and rs2285053, and BC risk. MATERIALS AND METHODS: MMP-2 genotypes were analyzed using PCR-based RFLP methodology in a...

Topics

Join the communities discussing this publication.

Breast Neoplasms
Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Predisposition to Disease

Genotype

Matrix Metalloproteinase 2

Polymorphism, Single Nucleotide

Promoter Regions, Genetic

Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 39191502
DOI: 10.21873/cgp.20467
PMCID: PMC11363925

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impacts of Matrix Metalloproteinase-2 Promoter Genotypes on Breast Cancer Risk.PMID 39191502Read ↗

Meta-analysis on the relationship between the SNP of MMP-2-1306 C>T and susceptibility to breast cancer.Semantic proximity Read ↗

Significant Association of Matrix Metalloproteinase-9 Polymorphisms With Triple Negative Breast Cancer RiskSemantic proximity Read ↗

The Association of Matrix Metalloproteinase-8 Promoter Genotypes in Breast Cancer.Semantic proximity Read ↗

Matrix metalloproteinase-2 polymorphisms and breast cancer susceptibility.Semantic proximity Read ↗

The MMP-2 -735 C allele is a risk factor for susceptibility to breast cancer.Semantic proximity Read ↗

Current evidence on the relationship between four polymorphisms in the matrix metalloproteinases (MMP) gene and breast cancer risk: a meta-analysis.Semantic proximity Read ↗

The MMP-1 Gene rs1799750 Polymorphism Is Associated with Breast Cancer Risk.Semantic proximity Read ↗

Prognostic impact of polymorphism of matrix metalloproteinase-2 and metalloproteinase tissue inhibitor-2 promoters in breast cancer in Tunisia: case-control study.Semantic proximity Read ↗

Association between four MMP-9 polymorphisms and breast cancer risk: a meta-analysis.Semantic proximity Read ↗

Substantial reduction in risk of breast cancer associated with genetic polymorphisms in the promoters of the matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 genes.Semantic proximity Read ↗

Association of single nucleotide polymorphisms in promoter of matrix metalloproteinase-2, 8 genes with bladder cancer risk in Northern India.Semantic proximity Read ↗

Matrix Metalloproteinase Gene Polymorphisms Are Associated with Breast Cancer in the Caucasian Women of Russia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.