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Article

Thermogenic characterization of ghrelin receptor null mice.

Methods in enzymology - 1 Jan 2012

Lin Ligen, Sun Yuxiang

Abstract excerpt

Ghrelin is the only known circulating orexigenic hormone that increases food intake and promotes adiposity, and these physiological functions of ghrelin are mediated through its receptor growth hormone secretagogue receptor (GHS-R). Ghrelin/GHS-R signaling plays a crucial role in energy homeostasis. Old GHS-R null mice exhibit a healthy phenotype-lean and insulin sensitive. Interestingly, the GHS-R null mice have...

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Identifiers

PMID: 22975064
DOI: 10.1016/B978-0-12-381272-8.00022-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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