Article
The Caenorhabditis elegans protein CTBP-1 defines a new group of THAP domain-containing CtBP corepressors.
Journal of molecular biology - 4 Jan 2008
Nicholas Hannah R, Lowry Jason A, Wu Tina, Crossley Merlin
Abstract excerpt
The C-terminal binding proteins (CtBPs) play roles in diverse cellular processes including transcriptional regulation, Golgi membrane fission, and synaptic ribbon formation. In the context of transcriptional regulation, they function as corepressors, interacting with promoter-bound transcription factors and recruiting a large protein complex that contains chromatin-modifying enzymes. We recently described the...
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