Article
Function of the C. elegans T-box factor TBX-2 depends on interaction with the UNC-37/Groucho corepressor.
Developmental biology - 1 Aug 2016
Huber Paul, Crum Tanya, Okkema Peter G
Abstract excerpt
T-box transcription factors are important regulators of development in all animals, and altered expression of T-box factors has been identified in an increasing number of diseases and cancers. Despite these important roles, the mechanism of T-box factor activity is not well understood. We have previously shown that the Caenorhabditis elegans Tbx2 subfamily member TBX-2 functions as a transcriptional repressor to...
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