Article
Eukaryotic ribosomal RNA determinants of aminoglycoside resistance and their role in translational fidelity.
RNA (New York, N.Y.) - 1 Jan 2008
Fan-Minogue Hua, Bedwell David M
Abstract excerpt
Recent studies of prokaryotic ribosomes have dramatically increased our knowledge of ribosomal RNA (rRNA) structure, functional centers, and their interactions with antibiotics. However, much less is known about how rRNA function differs between prokaryotic and eukaryotic ribosomes. The core decoding sites are identical in yeast and human 18S rRNAs, suggesting that insights obtained in studies with yeast rRNA...
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