Article
Mutations in yeast ribosomal proteins S28 and S4 affect the accuracy of translation and alter the sensitivity of the ribosomes to paromomycin.
Biochimica et biophysica acta - 11 Nov 1996
Synetos D, Frantziou C P, Alksne L E
Abstract excerpt
Ribosomal proteins S12, S5 and S4 of Escherichia coli are essential for the control of translational accuracy. Their yeast equivalents, i.e., S28, S4 and S13, have also been implicated in this process. Using a poly(U)-dependent cell-free translation system, we determined the accuracy of translation and the sensitivity to antibiotic paromomycin of yeast ribosomes carrying mutant ribosomal proteins S28 and/or S4....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
