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Article

Translational fidelity mutations in 18S rRNA affect the catalytic activity of ribosomes and the oxidative balance of yeast cells.

Biochemistry - 21 Mar 2006

Konstantinidis Theodoros C, Patsoukis Nikolaos, Georgiou Christos D, Synetos Dennis

Abstract excerpt

The function of mutations rdn1A, rdn1T, and rdn2 in 18S rRNA of Saccharomyces cerevisiae is investigated. The mutations correspond to substitutions C1054A, C1054U in helix 34, and G517A in helix 18 of 16S rRNA in Escherichia coli, respectively, in which the first and third mutations caused nonsense suppression, while C1054U caused no suppression. In yeast, rdn1A caused phenotypic suppression at nonsense codons,...

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Share to Catalysis
Share to Codon, Terminator

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Peptide Chain Initiation, Translational

Share to Peptidyl Transferases

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Share to RNA, Ribosomal, 18S

Share to RNA, Transfer, Amino Acyl

Share to Suppression, Genetic

Source

Identifiers

PMID: 16533033
DOI: 10.1021/bi052505d

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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