Article
Natural Colonization with Helicobacter species and the Development of Inflammatory Bowel Disease in Interleukin‐10‐deficient Mice
16 May 2005
Abstract excerpt
BACKGROUND: The interleukin-10-deficient (IL-10-/-) mice maintained in specific-pathogen-free (SPF) conditions develop typhlocolitis when experimentally infected with Helicobacter species. However, there is limited information regarding the role of Helicobacter species that naturally colonize IL-10-/- mice in typhlocolitis development. The aim of this study was to examine in SPF IL-10-/- mice the association...
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