Article

Long-read RNA sequencing identifies region- and sex-specific C57BL/6J mouse brain mRNA isoform expression and usage

2024-01-11

Abstract excerpt

Alternative splicing (AS) contributes to the biological heterogeneity between species, sexes, tissues, and cell types. Many diseases are either caused by alterations in AS or by alterations to AS. Therefore, measuring AS accurately and efficiently is critical for assessing molecular phenotypes, including those associated with disease. Long-read sequencing enables more accurate quantification of differentially spli...

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Literature Corpus work: 6e6929f7-a847-567e-8cce-fea4f805796a
DOI: 10.1101/2024.01.11.575219

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