Article
STAT1 gene variations, IgE regulation and atopy.
Allergy - 1 Dec 2007
Pinto L A, Steudemann L, Depner M, Klopp N, Illig T, Weiland S K, von Mutius E, Kabesch M
Abstract excerpt
BACKGROUND: Signal transducer and activator of transcription 1 (STAT1), an intracellular signal transducer and activator of transcription centrally involved in many inflammatory pathways, was recently suggested to play an important role in allergy related immune responses. AIM: Thus, we investigated the effect of polymorphisms in the STAT1 gene on the development of atopic sensitization and allergic diseases....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
