Article
Linkage and association studies of STAT6 gene polymorphisms and allergic diseases.
International archives of allergy and immunology - 1 May 2003
Tamura Kazushi, Suzuki Michiko, Arakawa Hirokazu, Tokuyama Kenichi, Morikawa Akihiro
Abstract excerpt
BACKGROUND: Signal transducer and activator of transcription 6 (STAT6) is a key transcription factor involved in both interleukin-4 (IL-4) and IL-13-mediated biological responses, such as allergies. Recently, we reported that the polymorphism of the STAT6 gene exon 1 was associated with allergic...
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