Article
Linkage and association studies of STAT6 gene polymorphisms and allergic diseases.
International archives of allergy and immunology - 1 May 2003
Tamura Kazushi, Suzuki Michiko, Arakawa Hirokazu, Tokuyama Kenichi, Morikawa Akihiro
Abstract excerpt
BACKGROUND: Signal transducer and activator of transcription 6 (STAT6) is a key transcription factor involved in both interleukin-4 (IL-4) and IL-13-mediated biological responses, such as allergies. Recently, we reported that the polymorphism of the STAT6 gene exon 1 was associated with allergic diseases, while another group studied the G2964A variant of the STAT6 gene's association with atopic asthma. We...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.