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Article

Interactive effect of STAT6 and IL13 gene polymorphisms on eczema status: results from a longitudinal and a cross-sectional study.

BMC medical genetics - 2 Jul 2013

Ziyab Ali H, Davies Gwyneth A, Ewart Susan, Hopkin Julian M, Schauberger Eric M, Wills-Karp Marsha, Holloway John W, Arshad Syed Hasan, Zhang Hongmei, Karmaus Wilfried

Abstract excerpt

BACKGROUND: Eczema is a prevalent skin disease that is mainly characterized by systemic deviation of immune response and defective epidermal barrier. Th2 cytokines, such as IL-13 and transcription factor STAT6 are key elements in the inflammatory response that characterize allergic disorders, including eczema. Previous genetic association studies showed inconsistent results for the association of single...

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Identifiers

PMID: 23815671
DOI: 10.1186/1471-2350-14-67
PMCID: PMC3700873

Genes

STAT6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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