Article
Association analysis of signal transducer and activator of transcription 4 (STAT4) polymorphisms with asthma.
Journal of human genetics - 1 Jan 2005
Park Byung Lae, Cheong Hyun Sub, Kim Lyoung Hyo, Choi Yoo Hyun, Namgoong Sohg, Park Hae-Sim, Hong Soo-Jong, Choi Byoung Whui, Lee June Hyuk, Park Choon-Sik, Shin Hyoung Doo
Abstract excerpt
The signal transducer and activator of transcription 4 (STAT4) on chromosome 2q32.2-q32.3 is known to be essential for mediating responses to interleukin 12 in lymphocytes and regulating the differentiation of T helper cells. In an effort to discover additional polymorphism(s) in genes in which variant(s) have been implicated in asthma, we investigated the genetic polymorphisms in STAT4 to evaluate it as a...
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